New and Emerging PAH Therapies and Approaches: A Mixture of Hope and Complexity

Hear experts discuss new and emerging therapies for PAH and find out why making the right diagnosis is key when determining your treatment approach.

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June 18, 2025
12:00 PM - 01:00 PM EDT
Virtual
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  • Overview

    Pulmonary arterial hypertension, or PAH, is a serious, progressive condition. Before developing a treatment approach, it’s imperative to make the correct diagnosis and consider patient comorbidities. Identifying which WHO Group patients are in is key, but part of the art of treating PAH is understanding that some patients may have overlap between groups. Developing an effective treatment plan is multifactorial, and treatment selection can involve the objective risk stratification score, cardiac functioning on imaging, and shared decision-making, among other considerations. Don’t miss out on expert insights to help you elevate your practice!

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Chair:
    Vallerie V. McLaughlin, MD
    Kim A. Eagle, MD, Endowed Professor of Cardiovascular Medicine
    Director, Pulmonary Hypertension Program
    University of Michigan Medical School
    Ann Arbor, MI

    Dr. McLaughlin has reported the following relevant financial relationships with ineligible companies during the past 24 months: 

    Advisor/Consultant: Aerami, Aerovate, Altavant, Apollo Therapeutics, Bayer, CorVista, CVS/Caremark, Gossamer Bio, Janssen, Keros, Merck, United Therapeutics, Vertex 
    Contracted Researcher: Aerovate, Altavant/Enzyvant, Gossamer Bio, Keros, Janssen, Merck/Acceleron, SoniVie 

    Faculty:
    Kelly Chin, MD 
    Director, Pulmonary Hypertension Clinical Research
    Director, Heart Lung Clinic 
    UT Southwestern Medical Center
    Dallas, TX 

    Dr. Chin has reported the following relevant financial relationships or relationships with ineligible companies for any amount during the past 24 months:

    Contracted Researcher: Gossamer Bio, Janssen, Merck, Untied Therapeutics
    Advisor/Consultant: Gossamer Bio, Janssen, Merck, Untied Therapeutics

    Ioana Preston, MD 
    Director, Pulmonary Hypertension Center
    Dept. of Pulmonary and Critical Care Medicine
    Lahey Hospital and Medical Center
    Burlington, MA

    Dr. Preston has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:

    Contracted Researcher: Acceleron/Merck, Actelion/Janssen, Keros, Liquidia, Respira, United Therapeutics
    Advisor/Consultant: Acceleron/Merck, Actelion/Janssen, Aerovate, Gossamer, Keros, Liquidia, Respira, United Therapeutics

    Reviewers/Content Planners/Authors: 

    • Cindy Davidson has no relevant relationships to disclose. 
    • Anita Galdieri, PharmD, has no relevant relationships to disclose.
    • Martha Kingman, NP, has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months: 
      • Advisor/Consultant: Aerami, Aerovate, Gossamer, Janssen, Liquidia, Merck
    • Brian P. McDonough, MD, FAAFP, has no relevant relationships to disclose. 
  • Learning Objectives

    Upon completion of this activity, learners should be better able to:

    • Discuss the importance of getting the correct pulmonary hypertension (PH) diagnosis
    • Evaluate the challenges and strategies for using new pulmonary arterial hypertension therapies with shared decision-making
    • Examine recent trial results in PH and discuss possible implications
  • Target Audience

    This activity has been designed to meet the educational needs of pulmonologists and cardiologists as well as all other physicians, physician assistants, nurse practitioners, nurses, pharmacists, and healthcare providers involved in managing patients with pulmonary hypertension (PH).  

  • Accreditation and Credit Designation Statements

     

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. 

    Global Learning Collaborative (GLC) designates this activity for 1.0 nursing contact hour(s). Nurses should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for 1.0 contact hour(s)/0.1 CEUs of pharmacy contact hour(s).

    The Universal Activity Number for this program is JA0006235-0000-25-053-L01-P. This learning activity is knowledge-based. Your CE credits will be electronically submitted to the NABP upon successful completion of the activity. Pharmacists with questions can contact NABP customer service (custserv@nabp.net). 

    Global Learning Collaborative (GLC) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit(s) for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit(s). Approval is valid until June 18, 2025. PAs should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)


    It’s about time! Today’s on-the-go learners have minutes to spend on education instead of hours. Total CME is an award-winning, global healthcare education company that strategically pioneers methodology, initiatives, and platforms to meet these time-limited needs. Unlike other medical education companies, Total CME employs a microlearning approach and platform to create outcome-based curricula that motivates HCPs to engage in self-directed point-of-care learning that impacts change in real time. Even while reaching the largest global distribution, we provide the most personalized, seamless learner experience. We’re meeting our busy learners where they are so they can focus on what they want when they need it, ultimately leading to behavior changes that impact clinical practice and empower patients in their own care.

  • Commercial Support

    This activity is supported by an independent educational grant from Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company of Johnson & Johnson.   

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Total CME, LLC. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to access a site outside of Total CME, LLC, you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site. 

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner. 

  • System Requirements

    • Supported Browsers (2 most recent versions):
      • Google Chrome for Windows, Mac OS, iOS, and Android
      • Apple Safari for Mac OS and iOS
      • Mozilla Firefox for Windows, Mac OS, iOS, and Android
      • Microsoft Edge for Windows
    • Recommended Internet Speed: 5Mbps+

Details
Presenters
  • Overview

    Pulmonary arterial hypertension, or PAH, is a serious, progressive condition. Before developing a treatment approach, it’s imperative to make the correct diagnosis and consider patient comorbidities. Identifying which WHO Group patients are in is key, but part of the art of treating PAH is understanding that some patients may have overlap between groups. Developing an effective treatment plan is multifactorial, and treatment selection can involve the objective risk stratification score, cardiac functioning on imaging, and shared decision-making, among other considerations. Don’t miss out on expert insights to help you elevate your practice!

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Chair:
    Vallerie V. McLaughlin, MD
    Kim A. Eagle, MD, Endowed Professor of Cardiovascular Medicine
    Director, Pulmonary Hypertension Program
    University of Michigan Medical School
    Ann Arbor, MI

    Dr. McLaughlin has reported the following relevant financial relationships with ineligible companies during the past 24 months: 

    Advisor/Consultant: Aerami, Aerovate, Altavant, Apollo Therapeutics, Bayer, CorVista, CVS/Caremark, Gossamer Bio, Janssen, Keros, Merck, United Therapeutics, Vertex 
    Contracted Researcher: Aerovate, Altavant/Enzyvant, Gossamer Bio, Keros, Janssen, Merck/Acceleron, SoniVie 

    Faculty:
    Kelly Chin, MD 
    Director, Pulmonary Hypertension Clinical Research
    Director, Heart Lung Clinic 
    UT Southwestern Medical Center
    Dallas, TX 

    Dr. Chin has reported the following relevant financial relationships or relationships with ineligible companies for any amount during the past 24 months:

    Contracted Researcher: Gossamer Bio, Janssen, Merck, Untied Therapeutics
    Advisor/Consultant: Gossamer Bio, Janssen, Merck, Untied Therapeutics

    Ioana Preston, MD 
    Director, Pulmonary Hypertension Center
    Dept. of Pulmonary and Critical Care Medicine
    Lahey Hospital and Medical Center
    Burlington, MA

    Dr. Preston has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:

    Contracted Researcher: Acceleron/Merck, Actelion/Janssen, Keros, Liquidia, Respira, United Therapeutics
    Advisor/Consultant: Acceleron/Merck, Actelion/Janssen, Aerovate, Gossamer, Keros, Liquidia, Respira, United Therapeutics

    Reviewers/Content Planners/Authors: 

    • Cindy Davidson has no relevant relationships to disclose. 
    • Anita Galdieri, PharmD, has no relevant relationships to disclose.
    • Martha Kingman, NP, has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months: 
      • Advisor/Consultant: Aerami, Aerovate, Gossamer, Janssen, Liquidia, Merck
    • Brian P. McDonough, MD, FAAFP, has no relevant relationships to disclose. 
  • Learning Objectives

    Upon completion of this activity, learners should be better able to:

    • Discuss the importance of getting the correct pulmonary hypertension (PH) diagnosis
    • Evaluate the challenges and strategies for using new pulmonary arterial hypertension therapies with shared decision-making
    • Examine recent trial results in PH and discuss possible implications
  • Target Audience

    This activity has been designed to meet the educational needs of pulmonologists and cardiologists as well as all other physicians, physician assistants, nurse practitioners, nurses, pharmacists, and healthcare providers involved in managing patients with pulmonary hypertension (PH).  

  • Accreditation and Credit Designation Statements

     

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. 

    Global Learning Collaborative (GLC) designates this activity for 1.0 nursing contact hour(s). Nurses should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for 1.0 contact hour(s)/0.1 CEUs of pharmacy contact hour(s).

    The Universal Activity Number for this program is JA0006235-0000-25-053-L01-P. This learning activity is knowledge-based. Your CE credits will be electronically submitted to the NABP upon successful completion of the activity. Pharmacists with questions can contact NABP customer service (custserv@nabp.net). 

    Global Learning Collaborative (GLC) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit(s) for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA Category 1 CME credit(s). Approval is valid until June 18, 2025. PAs should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)


    It’s about time! Today’s on-the-go learners have minutes to spend on education instead of hours. Total CME is an award-winning, global healthcare education company that strategically pioneers methodology, initiatives, and platforms to meet these time-limited needs. Unlike other medical education companies, Total CME employs a microlearning approach and platform to create outcome-based curricula that motivates HCPs to engage in self-directed point-of-care learning that impacts change in real time. Even while reaching the largest global distribution, we provide the most personalized, seamless learner experience. We’re meeting our busy learners where they are so they can focus on what they want when they need it, ultimately leading to behavior changes that impact clinical practice and empower patients in their own care.

  • Commercial Support

    This activity is supported by an independent educational grant from Actelion Pharmaceuticals US, Inc., a Janssen Pharmaceutical Company of Johnson & Johnson.   

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Total CME, LLC. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to access a site outside of Total CME, LLC, you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site. 

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner. 

  • System Requirements

    • Supported Browsers (2 most recent versions):
      • Google Chrome for Windows, Mac OS, iOS, and Android
      • Apple Safari for Mac OS and iOS
      • Mozilla Firefox for Windows, Mac OS, iOS, and Android
      • Microsoft Edge for Windows
    • Recommended Internet Speed: 5Mbps+

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